Twice-Daily Dosing1
Starting Dose231 mg twice daily (Days 1-7) |
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Maintenance Dose462 mg twice daily (After Day 7) |
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For individuals who cannot tolerate the maintenance dose, a temporary dosage reduction to 231 mg twice a day may be considered
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- Within 4 weeks, the recommended dosage of 462 mg twice a day should be resumed
- Discontinuation of VUMERITY should be considered for patients unable to tolerate return to the maintenance dosage
Administration instructions
- VUMERITY should be swallowed whole and intact
- VUMERITY should not be crushed or chewed, and the capsule contents should not be sprinkled on food
- If taken with food, a high-fat, high-calorie meal/snack should be avoided (the meal/snack should contain no more than 700 calories and no more than 30 g fat)
- Avoid co-administration of VUMERITY with alcohol
- No dosing adjustment is recommended in patients with mild renal impairment
- VUMERITY is not recommended in patients with moderate or severe renal impairment
Speak to your patients about the importance of adherence when taking VUMERITY